Origin of the pandemic 1957 H2 influenza A viruses and the persistence of its possible progenitors in the avian reservoir
Identifieur interne : 001F18 ( Main/Exploration ); précédent : 001F17; suivant : 001F19Origin of the pandemic 1957 H2 influenza A viruses and the persistence of its possible progenitors in the avian reservoir
Auteurs : J. R. Sch Fer [États-Unis] ; Yoshihiro Kawaoka [États-Unis] ; W. J. Bean [États-Unis] ; J. Süss ; D. Senne ; R. G. Webster [États-Unis]Source :
- Virology : (New York, NY) [ 0042-6822 ] ; 1993.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
Abstract
H2N2 influenza A viruses caused the Asian pandemic of 1957 and then disappeared from the human population 10 years later. To assess the potential for similar outbreaks in the future, we determined the antigenicity of H2 hemagglutinins (HAs) from representative human and avian H2 viruses and then analyzed the nucleotide and amino acid sequences to determine their evolutionary characteristics in different hosts. The results of longitudinal virus surveillance studies were also examined to estimate the prevalence of avian H2 isolates among samples collected from wild ducks and domestic poultry. Reactivity patterns obtained with a large panel of monoclonal antibodies indicated antigenic drift in the HA of human H2 influenza viruses, beginning in 1962
Affiliations:
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To assess the potential for similar outbreaks in the future, we determined the antigenicity of H2 hemagglutinins (HAs) from representative human and avian H2 viruses and then analyzed the nucleotide and amino acid sequences to determine their evolutionary characteristics in different hosts. The results of longitudinal virus surveillance studies were also examined to estimate the prevalence of avian H2 isolates among samples collected from wild ducks and domestic poultry. Reactivity patterns obtained with a large panel of monoclonal antibodies indicated antigenic drift in the HA of human H2 influenza viruses, beginning in 1962</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Wisconsin</li></region><settlement><li>Madison (Wisconsin)</li></settlement><orgName><li>Université du Wisconsin à Madison</li></orgName></list><tree><noCountry><name sortKey="Senne, D" sort="Senne, D" uniqKey="Senne D" first="D." last="Senne">D. 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